Resident Evil 0: HD Remaster takes players back to the origins of the infamous Mansion Incident, following rookie S.T.A.R.S. officer Rebecca Chambers and escaped convict Billy Coen as they struggle to survive a deadly outbreak in the remote Arklay Mountains. Trapped aboard a mysterious train and later drawn into a sinister research facility, the duo uncovers the dark secrets behind the Umbrella Corporation’s terrifying experiments. As they face grotesque creatures, deadly puzzles, and growing danger at every turn, Rebecca and Billy must learn to trust each other to stay alive. Blending suspense, survival horror, and rich storytelling, the game reveals crucial events that set the stage for the entire Resident Evil saga.